Polyethylene glycol 400 (PEG 400) is a low-molecular-weight grade of polyethylene glycol. It is very hydrophilic, which renders it a useful ingredient in drug formulations to augment the solubility and bioavailability of weakly water-soluble drugs.
This chemical is used as suitable auxiliary factor in paper, leather and coating industries. This chemical is also used as flocculent, cement suspension factor and as emulsifier in different industries.
Synonoms : Polyglycol, Polyethylene oxide, Polyoxy ethylene, PEG 400 PEG, poly(oxyethylene), poly(ethylene oxide)
| Appearance (Clarity) | Clear |
| Appearance (Colour) | Colourless |
| Appearance (Form) | Viscous liquid |
| Density (g/ml) @ 20°C | 1.120 - 1.126g/ml |
| Viscosity (20°C) | ~ 120 mPa |
| Average Molecular weight | 380 -420 |
| Acidity (CH3COOH) | max. 0.05% |
| Boiling point | >200 degree C |
| Flash Point | 138.6 degree C |
| pH Value | 5-7 |
| Purity | 99 |
| EC No | 500-038-2 |
| CAS No | 25322-68-3 |
PEG 400 HSN Code : 34042000
Storage : Room Temperature
Shelf Life : 60 Months
| Product Name | RXSOL-81-8123-210 |
| Product Type | Polyethylene Glycol 400 (PEG 400) |
Company Details:
RX MARINE INTERNATIONAL
105, A wing , BSEL , TECH PARK.
VASHI ,NEW BOMBAY 400703 INDIA
| Phone | +91 22 65113333 / 5555 / 9999 |
| Fax | +91 22 2781 1318 :::AOH :0091 9821214367 |
| care@rxmarine.com |
| Name | CAS # | % by Weight |
| Polyethylene glycol 400 | 25322-68-3 | 100 |
| Skin contact | irritant |
| Eye contact | irritant |
| Mutagenic effect | NA |
| Teratogenic Effect | NA |
| Developmental Toxicity | NA |
|
Eye Contact |
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Cold water may be used. Get medical attention if irritation occurs. |
|
Skin Contact |
Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops. Cold water may be used. |
|
Serious Skin Contact |
Not available. |
|
Inhalation |
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention. |
| Serious Inhalation | Not available. |
| Ingestion | Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar, tie, belt or waistband. |
| Serious Ingestion | Not available. |
| Flammability of the Product | May be combustible at high temperature. |
| Auto-Ignition Temperature | Not available. |
| Flash Points | CLOSED CUP: 226.67°C (440°F). OPEN CUP: 231.11°C (448°F) |
| Flammable Limits | Not available. |
| Products of Combustion | These products are carbon oxides (CO, CO2). |
| Fire Hazards in Presence of Various Substances | Slightly flammable to flammable in presence of open flames and sparks of heat. |
| Risks of explosion of the product in presence of mechanical impact | Not available. |
|
Risks of explosion of the product in presence of static discharge |
Not available. |
| Fire Fighting Media and Instructions: | |
| SMALL FIRE | Use DRY chemical powder. |
| LARGE FIRE | Use water spray, fog or foam. Do not use water jet. |
| Special Remarks on Fire Hazards | Not available. |
| Special Remarks on Explosion Hazards | Not available. |
|
Small Spill |
Dilute with water and mop up, or absorb with an inert dry material and place in an appropriate waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements. |
|
Large Spill |
Absorb with an inert material and put the spilled material in an appropriate waste disposal. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system. Be careful that the product is not present at a concentration level above TLV. Check TLV on the MSDS and with local authorities. |
|
Precautions |
Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not ingest. Do not breathe gas/fumes/ vapor/spray. Wear suitable protective clothing. If ingested, seek medical advice immediately and show the container or the label. Keep away from incompatibles such as oxidizing agents, acids, alkalis. |
| Storage | Keep container tightly closed. Keep container in a cool, well-ventilated area. |
|
Engineering Controls |
Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their respective threshold limit value. Ensure that eyewash stations and safety showers are proximal to the work-station location. |
| Personal Protection |
Safety glasses. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Gloves. |
| Personal Protection in Case of a Large Spill |
Splash goggles. Full suit. Vapor respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product. |
| Exposure Limits | TWA: 10 (mg/m3) from AIHA Consult local authorities for acceptable exposure limits. |
| Average Molecular Weight | 380 - 420 |
| Freezing point | 39 - 46 Deg F |
| Flash point | 435 Deg F |
| Fire point | 510 Deg F |
| Specific gravity |
d 60 / 60= 1.125 d 248 / 60= 1.050 |
| Viscosity |
@ 120Deg F 30.7 cp @ 248Deg F 5.5 cp |
| Water Solubility | solible |
| pH (5 % aqueous) |
4.5-7.5 (5% soln) |
| Specific Heat , BTU /lb Deg F |
@ 120 Deg F 0.494 @ 248 DegF 0.543 |
| Physical state and appearance | Liquid. ( viscous) |
| Odor | Odorless. |
| Taste | Not available. |
| Color | Clear |
| Boiling Point | Not available. |
| Melting Point | 4°C (39.2°F) - 6 C. |
| Critical Temperature | Not available. |
| Vapor Pressure | Not available. |
| Vapor Density | Not available. |
| Volatility | Not available. |
| Odor Threshold | Not available. |
| Water/Oil Dist. Coeff. | Not available. |
| Ionicity (in Water) | Not available. |
| Stability |
The product is stable. |
|
Instability Temperature |
Not available. |
|
Conditions of Instability |
Incompatible materials (strong oxiders), excess heat. |
|
Incompatibility with various substances |
Reactive with oxidizing agents, acids, alkalis. |
|
Corrosivity |
Non-corrosive in presence of glass. |
| Special Remarks on Reactivity | Slightly Hygroscopic |
| Special Remarks on Corrosivity | Not available. |
| Polymerization | Will not occur |
| Routes of Entry |
Absorbed through skin. Eye contact. |
| Toxicity to Animals | |
| Acute oral toxicity (LD50) | 26800 mg/kg [Rabbit]. |
| Acute dermal toxicity (LD50) | >20000 mg/kg [Rabbit] |
|
Acute toxicity of the vapor (LC50) |
>13 8 hours [Rat]. |
| Chronic Effects on Humans | Not available. |
| Other Toxic Effects on Humans | Slightly hazardous in case of skin contact (irritant, permeator), of ingestion, of inhalation. |
| Special Remarks on Toxicity to Animals | Not available. |
| Special Remarks on Chronic Effects on Humans | Not available. |
| Special Remarks on other Toxic Effects on Humans: | |
| Acute Potential Health Effects: | |
| Skin |
It may cause mild skin irritation. It may be absorbed through the skin, but absorption of harmful amounts is unlikely. |
| Eyes | It may cause mild eye irritation. |
| Inhalation | At room temperature, exposure to vapor is minimal due to low volatility. A single exposure is not likely to be hazardous. |
| Ingestion | Low toxicity. Harmful effects not anticipated from swallowing small amounts. Ingestion of larger amounts may cause nausea, vomiting, cardiac arrhythmias, hypotension. It may also affect the urinary system. Prolonged or repeated ingestion may affect metabolism (weight loss). |
| Ecotoxicity | Ecotoxicity in water (LC50): >5000 mg/l 24 hours [Goldfish]. |
| BOD5 and COD | Not available |
| Products of Biodegradation | Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise. |
| Toxicity of the Products of Biodegradation | The products of degradation are less toxic than the product itself. |
| Special Remarks on the Products of Biodegradation | Not available. |
|
Waste Disposal |
Waste must be disposed of in accordance with federal, state and local environmental control regulations. |
|
DOT Classification |
Not regulated |
| Identification | Not applicable. |
| Special Provisions for Transport | Not applicable. |
|
Federal and State Regulations |
Not regulated |
| Minnesota | Polyethylene glycol 400 TSCA 8(b) |
| inventory | Polyethylene glycol 400 |
| Other Regulations | Not available. |
| Other Classifications | |
| WHMIS (Canada) | Not controlled under WHMIS (Canada). |
| DSCL (EEC) | Not Available S24/25- Avoid contact with skin and eyes. |
| HMIS (U.S.A.) | |
| Health Hazard | 1 |
| Fire Hazard | 1 |
| Reactivity | 0 |
| Personal Protection | g |
| National Fire Protection Association (U.S.A.) | |
| Health | 0 |
| Flammability | 1 |
| Reactivity | 0 |
| Specific hazard | |
| Protective Equipment | Gloves. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Safety glasses. |
The information contained in this safety data sheet is given in good faith. It is accurate to the best of our The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall rxsol be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if rxsol has been advised of the possibility of such damages.
DISCLAIMER OF LIABILITY :The information in this SDS was obtained from sources which we believe are reliable. However, the information is provided without any warranty, express or implied, regarding its correctness. The conditions or methods of handling, storage, use or disposal of the product are beyond our control and may be beyond our knowledge. For this and other reasons, we do not assume responsibility and expressly disclaim liability for loss, damage or expense arising out of or in any way connected with the handling, storage, use or disposal of the product. This MSDS was prepared and is to be used only for this product. If the product is used as a component in another product, this MSDS information may not be applicable.