Propylene glycol is a humectant, which means that it is an ingredient that is added to cosmetics to increase Moisture Retention in skin and hair. Propylene glycol is well tolerated by the skin and shouldn't cause redness or irritation.
It is used to absorb extra water and maintain moisture in certain medicines, cosmetics, or food products. It is a solvent for food colors and flavors, and in the paint and plastics industries. Propylene glycol is also used to create artificial smoke or fog used in fire-fighting training and in theatrical productions.
According to the Material Safety Data Sheet on propylene glycol, the chemical is a strong skin irritant, and has been implicated in contact dermatitis.
Description: Propylene Glycol USP
|
Test Description |
Specification Limits Min. Max. |
Unit of Measure |
Test Method |
|
|
Propylene Glycol, on a Dry basis |
99.5 |
%(w/w) |
HOC 0540 |
|
|
Acidity as acetic acid |
0.002 |
%(w/w) |
HOC 0210 |
|
|
Chlorides |
0.5 |
ppm |
HOC 0221 |
|
|
Colour, Pt-Co |
10 |
APHA Colour |
HOC 0641 |
|
|
Heavy Metals as Pb |
5 |
ppm |
HOC 0274 |
|
|
Iron |
0.5 |
ppm |
HOC 0290 |
|
|
Water |
0.2 |
%(w/w) |
HOC 0316 |
|
|
Arsenic as As |
1 |
HOC 0242 |
||
|
Distillation @ 760 mm Hg |
||||
|
Initial Boiling Point |
186 |
oC |
HOC 0154 |
|
|
Drying Point |
189 |
oC |
HOC 0154 |
|
|
Residue on Ignition |
0 |
0.005 |
%(w/w) |
HOC 0140 |
|
Specific Gravity@20/20 oC |
1.0377 |
1.0389 |
HOC 0132 |
|
|
Specific Gravity@25/25 oC |
1.0352 |
1.0364 |
HOC 0132 |
|
|
Sulphate |
0 |
0.006 |
%(w/w) |
HOC 0225 |
Propylene glycol is tolerated well by the skin and shouldn't cause redness or irritation. Propylene glycol is a penetration-enhancing humectant.
Propylene Glycol USP is a widely used ingredient in pharmaceutical, food, cosmetic, personal care, flavors and animal feed applications; an overview of typical uses of Propylene Glycol USP as below.It must be emphasized that it is the user’s responsibility to consult area and country-specific regulations for details of approved use.
-
Pharmaceuticals - Solvent for active ingredients in oral, and topical products.
-
Cosmetics & Personal Care - Solvent, coupling agent, carrier, emulsion stabilizer, softening agent, viscosity modifier and humectant in many types of cosmetics and personal care products such as skincare, sun care, shampoo, bath/shower products, toothpastes, mouthwashes, shaving products and baby care products.
-
Flavors & Fragrances - Solvent and extraction solvent of flavors and fragrances for applications in food, beverages, perfumes and cosmetics.
-
Food - Various applications as a direct food additive (E 1520) such as a carrier or carrier solvent for colors, emulsifiers, antioxidants and enzymes (in Europe with maximum 1 g/kg in human foodstuffs), and humectant and stabilizer in fruits, vegetables and bakery goods (except in Europe). Propylene Glycol USP is also applied in indirect contact food applications, such as a low temperature heat-transfer fluid in the brewing, dairy and ice cream industries and for food storage facilities, an equipment cleaner fluid or a solvent for printing inks.
- Pet foods & Animal Feed - Humectant, emulsifier, preservative, solvent foradditives, energy source and aid for prevention of ketosis (acetonemia) in dairycattle. In EMEA a specific tailor made Propylene Glycol Animal Feed is offered forthis application.
Propylene Glycol USP, is a high-purity grade of monopropylene glycol for use in pharmaceutical, food, cosmetic, personal care, flavor and fragrance, plus a variety of other applications.It is a light, transparent liquid, almost odorless and with low volatility. It is completely soluble in water and in most organic solvents. In addition, all propylene glycols have a great capacity to hold and dissolve active ingredients equally which allows them to serve as carriers of aromas, flavors, dyes and moisture.
Propylene Glycol USP is tested for compliance with the current USP, EP, and Japanese Pharmacopoeia (JP) specifications plus the Food Chemical Codex (FCC); it also complies with the Brazilian Pharmacopoeia, and other pharmaceutical, cosmetic and food regulations in the global markets where it is sold. It is listed by the Cosmetic, Toiletry and Fragrance Association as an approved ingredient in cosmetics and its use is reviewed by the Cosmetic Ingredient Review (CIR). Propylene Glycol USP is Kosher certified and complies with Halal requirements.

| Product Name | RXSOL-19-1586-210 |
| Product Type | Mono Propylene Glycol USP/IND |
Company Details:
RX MARINE INTERNATIONAL
105, A wing , BSEL , TECH PARK.
VASHI ,NEW BOMBAY 400703 INDIA
Stock Point : Mumbai, Kandla, Chennai, Visakhapatnam, Kolkata, Fujairah, Muscat, Canada, Nairobi
| Phone | +91 22 65113333 / 5555 / 9999 / 27815540/41 |
| Fax | +91 22 2781 1318 :::AOH :0091 9821214367 |
| mail@rxmarine.com |

|
Chemical Name |
CAS Number |
EC Number |
|
Propane-1,2-diol |
57-55-6 |
200-338-0 |

Hazard description: Not applicable.
Information concerning particular hazards for human and environment: Not applicable.

| General information | No special measures required. |
|
After inhalation |
Supply fresh air; consult doctor in case of complaints. |
|
After skin contact |
Generally the product does not irritate the skin. |
|
After eye contact |
Rinse opened eye for several minutes under running water. |
|
After swallowing |
If symptoms persist consult doctor. |

Suitable extinguishing agents: Use fire extinguishing methods suitable to surrounding conditions.
Protective equipment: No special measures required.

6.1 Personal Precautions, Protective Equipment and Emergency Procedures
No special personal safety precautions are normally required for small quantities under normal conditions of use. Avoid unnecessary contact with the spilled product and use appropriate personal protective equipment where prolonged contact or large-scale spills are involved.
6.2 Environmental Precautions
Dilute with plenty of water where appropriate and safe to do so. Do not allow the undiluted product or large quantities of the material to enter sewers, surface water or ground water. Prevent uncontrolled release into the environment.
6.3 Methods and Material for Containment and Cleaning Up
Contain the spill and collect the material using suitable liquid-binding/absorbent materials, such as:
-
Sand
-
Diatomite
-
Acid binders
-
Universal binders
-
Sawdust
Collect the absorbed material into suitable, properly labelled containers for appropriate disposal in accordance with applicable local regulations. Clean the affected area with water after removal of the spilled material, while preventing contaminated wash water from entering drains or watercourses.
6.4 Additional Information
Under normal conditions of use and handling, no dangerous substances are released. Avoid uncontrolled discharge of concentrated product into drains or natural water systems.

Handling:
Information for safe handling:
Handling:
Information for safe handling: No special requirement
Information about fire - and explosion protection: No special measures required.
Storage:
Requirements to be met by storerooms and receptacles: No special requirements.
Information about storage in one common storage facility: Not required.
Further information about storage conditions: None.
Information about fire - and explosion protection: No special measures required.
Storage:
Requirements to be met by storerooms and receptacles: No special requirements.
Information about storage in one common storage facility: Not required.
Further information about storage conditions: None.

Additional information about design of technical facilities: No further data; see item 7.
| Ingredients with limit values that require monitoring at the workplace: | |
| 57-55-6 propane-1,2-diol | |
|
WEEL (USA) WEL (Great Britain) |
10 mg/m³ 474* 10** mg/m³, 150* ppm *total vapour and particulates **particulates |
Additional information: The lists valid during the making were used as basis.
Personal protective equipment:
General protective and hygienic measures:
The usual precautionary measures are to be adhered to when handling chemicals.
Respiratory protection: Not required.
Protection of hands: The glove material has to be impermeable and resistant to the product/ the substance/ the preparation. Due to missing tests no recommendation to the glove material can be given for the product/ the preparation/ the chemical mixture. Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation
Material of gloves:The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and
varies from manufacturer to manufacturer.
Penetration time of glove material:The exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed.
Eye protection: Goggles recommended during refilling.

|
General Information |
|
|
Form |
Fluid |
|
Colour |
Colourless |
|
Odour |
Nearly Odourless |
|
Change in condition |
|
|
Melting point/Melting range |
-68°C |
|
Boiling point/Boiling range |
185°C |
|
Flash point |
> 100°C |
|
Ignition temperature |
371°C |
| Danger of explosion | Product does not present an explosion hazard. |
| Explosion limits | |
| Lower | 2.6 Vol % |
| Upper | 12.6 Vol % |
| Vapour pressure at 20°C | 0.11 hPa |
| Density at 20°C | 1.0362 g/cm³ |
| Solubility in / Miscibility with water | Fully miscible. |
| pH-value (- g/l) | neutral |
| Viscosity | |
| Dynamic at 25°C | 46 mPas |

Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.
Dangerous reactions No dangerous reactions known.
Dangerous decomposition products: No dangerous decomposition products known.

| Acute toxicity: | |||||
| LD/LC50 values relevant for classification: | |||||
|
Oral Dermal |
LD50 LD50 |
2000 mg/kg (rat) 20800 mg/kg (rabbit) |
|||
| Primary irritant effect: | |||||
| on the skin | No irritant effect. | ||||
| on the eye | No irritating effect. | ||||
| Sensitization | No sensitizing effects known. | ||||
| Additional toxicological information: | |||||
|
When used and handled according to specifications, the product does not have any harmful effects to our experience and the information provided to us. The substance is not subject to classification according to the latest version of the EU lists. |
|||||

General notes: Water hazard class 1 (German Regulation) (Assessment by list): slightly hazardous for water Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system.

Product:
Recommendation Smaller quantities can be disposed of with household waste.
Uncleaned packaging:
Recommendation: Disposal must be made according to official regulations.
Recommended cleansing agents: Water, if necessary together with cleansing agents.

Land transport ADR/RID (cross-border)
ADR/RID class: -
Maritime transport IMDG:
IMDG Class: -
Marine pollutant: No
Air transport ICAO-TI and IATA-DGR:
ICAO/IATA Class: -

Labelling according to EU guidelines:
Observe the general safety regulations when handling chemicals.
The substance is not subject to classification according to EU lists and other sources of literature known to us.

This information is based on our present knowledge.However, this shall not constitute a guarantee for anys pecific product features and shall not establish a legally valid contractual relationship.
DISCLAIMER OF LIABILITY :The information in this SDS was obtained from sources which we believe are reliable. However, the information is provided without any warranty, express or implied, regarding its correctness. The conditions or methods of handling, storage, use or disposal of the product are beyond our control and may be beyond our knowledge. For this and other reasons, we do not assume responsibility and expressly disclaim liability for loss, damage or expense arising out of or in any way connected with the handling, storage, use or disposal of the product. This MSDS was prepared and is to be used only for this product. If the product is used as a component in another product, this MSDS information may not be applicable.